Lung Texture


CE Mark Certified, Investigational Use Only in the U.S.


High resolution CT (HRCT) is a vital diagnostic tool for fibrotic conditions.1 Diagnostic accuracy is essential for optimal patient care decisions, but readers often disagree.2 Even with modern HRCT, imaging diagnosis remains challenging. Studies show that diagnostic accuracy for ILD’s varies greatly between readers3 and there is poor agreement among physicians in noting findings on CT imaging indicative of fibrotic conditions.4


Lung Texture Analysis ™ from Imbio applies advanced computer vision to transform a standard chest CT into a detailed map of the lung textures that are key to identifying ILD’s and other fibrotic conditions (normal, ground glass, reticular, honeycomb and hyperlucent). LTA’s DICOM image series provides an intuitive texture overlay on the patient scan to highlight abnormalities and increase diagnostic confidence.

LTA’s physician summary report provides detailed quantification of the textures by lung region to help reduce reading variation, and enable data-based decisions for drug therapy, clinical procedures and other personalized patient care.

Fully Automated Efficiency

Imbio is unique in delivering full quantitative analysis and 3D visualization without added work for radiology. LTA is fully automated and inserts results directly into the patient study in your PACS in just minutes.

LEARN MORE more about imbio’s fully automaed processing


MAYO logo Imbio works with the most trusted names in healthcare to bring breakthrough image analysis to daily clinical care. Lung Texture Analysis™ is based on the highly regarded CALIPER technology pioneered at the Mayo Clinic, Rochester.

In published studies, CALIPER has been shown to produce results comparable to expert radiologic judgment. “It is effective in the classification of normal versus abnormal tissue and performs as well as the experts in distinguishing among typical pathologies present in lungs with UIP/IPF.” 5

1. Gotway MB, et al. Challenges in pulmonary fibrosis: Use of high resolution CT scanning of the lung for the evaluation of patients with idiopathic interstitial pneumonias. Thorax. 2007 Jun; 62(6): 546–553.
2. Wells AU. The revised ATS/ERS/JRS/ALAT diagnostic criteria for idiopathic pulmonary fibrosis (IPF) - practical implications. Respiratory Research. 2013;14(Suppl 1):S2.
3. VB Antunes et al Observer Agreement in the diagnosis of Interstitial Lung Diseases based on HRCT scans. Bras Pneumol 36(1), 29-36 Jan-Feb 2010
4. Jacob J Automated Quantitative Computed Tomography versus Visual Computed Tomography Scoring in Idiopathic Pulmonary Fibrosis: Validation Against Pulmonary Function. J Thoracic Imaging 2016. Sept: 31(5):304-11
5. Zavaletta VA, Bartholmai BJ, et al. High Resolution Multi-Detector CT Aided Tissue Analysis and Quantification of Lung Fibrosis. Acad Radiol. 2007 July; 14(7): 772–787.
6. Bartholomai et al. Quantitative CT Imaging of Interstitial Lung Diseases. J Thoracic Imaging 2013 Sept 28(5)
7. Imbio company sponsored study with fellowship-trained thoracic radiologists. 2016.